Cryoanalgesia in Interventional Pain Management A Focused Review

Funding: There was no external funding in prepara-tion of this manuscript. Cryoneuroablation, also known as cryo-analgesia or cryoneurolysis, is a specialized technique for providing long-term pain relief in interventional pain management settings. Modern cryoanalgesia traces its roots to Coo-per et al who developed in 1961, a device that used liquid nitrogen in a hollow tube that was insulated at the tip and achieved a temperature of- 190 ° C. Lloyd et al proposed that cryoanal-gesia was superior to other methods of periph-eral nerve destruction, including alcohol neu-rolysis, phenol neurolysis, or surgical lesions. The application of cold to tissues creates a con