Add to ORKGAbstract: Familial paragangliomas of the neck are often bilat-eral and more aggressive than spontaneous forms. Tumors appear earlier (2nd–4th decade) often with diffuse, multifocal involvement. Without treatment, these tumors can lead to signifi-cant morbidity. Three families with succinate dehydrogenase subunit D (SDHD) germline mutations underwent clinical and genetic evaluation. Patients were screened using ultrasound and evaluated further with conventional and functional imaging. Tumors with a diameter>1.5 cm were surgically removed. Multi-centric and bilateral tumors were detected in 9/13 (69%) and 8/ 13 (62%) patients, respectively. Surgical morbidity occurred in 64 % of patients. Local recurrence was 57%, although this was lower i...
Background The hereditary paraganglioma syndromes (PGLs) are autosomal dominant conditions with an ...
Abstract: Background. The hereditary paraganglioma syn-dromes (PGLs) are autosomal dominant conditio...
Head and neck paragangliomas (HNPGLs) are neural crest-derived tumors. In comparison with paragangli...
BACKGROUND: The purpose of this study was to investigate clinical features and prevalence of germlin...
BACKGROUND: The purpose of this study was to give an overview on hereditary syndromes associated wit...
Paragangliomas are rare tumors of neural crest origin. They are benign in the majority of cases and ...
Head and neck paraganglioma (HNPGL) are rare, highly vascular; typically slow growing and mostly ben...
Background: Head and neck paraganglioma (PGL) are benign tumors that can cause important direct or s...
Head and neck paraganglioma is a rare tumour, especially in its familial form. We report a case of a...
Context: Familial paraganglioma of the head and neck (HNP) has been a known entity for decades but h...
Background: Germline mutations in the succinate dehydrogenase B (SDHB) gene predispose to hereditary...
BACKGROUND: Hereditary head and neck paragangliomas (HNP) are very often associated with pheochromoc...
Paragangliomas are rare neoplasms that occur predominantly in the head and neck region. They origina...
BACKGROUND: Early detection of paragangliomas (PGs) has been linked to low morbidity after surgical ...
Head and neck paragangliomas are tumors arising from specialized neural crest cells. Prominent locat...
Background The hereditary paraganglioma syndromes (PGLs) are autosomal dominant conditions with an ...
Abstract: Background. The hereditary paraganglioma syn-dromes (PGLs) are autosomal dominant conditio...
Head and neck paragangliomas (HNPGLs) are neural crest-derived tumors. In comparison with paragangli...
BACKGROUND: The purpose of this study was to investigate clinical features and prevalence of germlin...
BACKGROUND: The purpose of this study was to give an overview on hereditary syndromes associated wit...
Paragangliomas are rare tumors of neural crest origin. They are benign in the majority of cases and ...
Head and neck paraganglioma (HNPGL) are rare, highly vascular; typically slow growing and mostly ben...
Background: Head and neck paraganglioma (PGL) are benign tumors that can cause important direct or s...
Head and neck paraganglioma is a rare tumour, especially in its familial form. We report a case of a...
Context: Familial paraganglioma of the head and neck (HNP) has been a known entity for decades but h...
Background: Germline mutations in the succinate dehydrogenase B (SDHB) gene predispose to hereditary...
BACKGROUND: Hereditary head and neck paragangliomas (HNP) are very often associated with pheochromoc...
Paragangliomas are rare neoplasms that occur predominantly in the head and neck region. They origina...
BACKGROUND: Early detection of paragangliomas (PGs) has been linked to low morbidity after surgical ...
Head and neck paragangliomas are tumors arising from specialized neural crest cells. Prominent locat...
Background The hereditary paraganglioma syndromes (PGLs) are autosomal dominant conditions with an ...
Abstract: Background. The hereditary paraganglioma syn-dromes (PGLs) are autosomal dominant conditio...
Head and neck paragangliomas (HNPGLs) are neural crest-derived tumors. In comparison with paragangli...