We have shown previously that human herpesvirus 8 (HHV-8)-infected dendritic cells (DCs) undergo incomplete maturation and have a defective antigen-presenting function. Here, we examined the effects of HHV-8 infection on cytokine production, which is critical to the function of DCs. We detected expression of interleukin (IL)-6, tumour necrosis factor (TNF)-a, macrophage inflammatory protein (MIP)-1a, MIP-1b, RANTES and IL-12p40 from 2 to 6 h post-infection, and these peaked by 15–24 h. Expression of these factors decreased 24–48 h post-infection, with the exception of TNF-a which remained high throughout the entire 72 h. Interestingly, while IL-12p40 expression increased post-infection, bioactive IL-12p70 was not detected in the supernatant...
Evidence indicates that, at least in the early stage, Kaposi's sarcoma (KS) is a cytokine-mediated d...
It is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarco...
Aim: To evaluate the gene expression changes that occur soon after the active infection of two susce...
Human herpesvirus-8 induces a wide range of inflammatory immune mediators known to contribute to its...
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesviru...
Human herpesvirus-8 (HHV-8, also known as Kaposi's sarcoma associated herpesvirus, KSHV) is a gamma-...
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesviru...
Several viruses interfere with the host immune response by infecting dendritic cells and by altering...
Human herpesvirus 8 (HHV-8) is a recently discovered gammaherpesvirus that is the etiologic agent of...
International audienceBACKGROUND: For an efficient immune response against viral infection, dendriti...
Several lines of evidence suggest that dendritic cells (DCs), the most potent antigen-presenting cel...
Herpesviruses infect most humans. Their infections can be associated with pathological conditions an...
BACKGROUND: Human herpesvirus-8 (HHV-8) is the etiological agent of Kaposi's sarcoma (KS) and of som...
Dissertation presented to obtain the Ph.D degree in BiologyHuman cytomegalovirus (HCMV) is a -herpe...
Human herpesvirus 8 (HHV-8) is a lymphotropic gammaherpesvirus that causes Kaposi's sarcoma (KS), a ...
Evidence indicates that, at least in the early stage, Kaposi's sarcoma (KS) is a cytokine-mediated d...
It is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarco...
Aim: To evaluate the gene expression changes that occur soon after the active infection of two susce...
Human herpesvirus-8 induces a wide range of inflammatory immune mediators known to contribute to its...
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesviru...
Human herpesvirus-8 (HHV-8, also known as Kaposi's sarcoma associated herpesvirus, KSHV) is a gamma-...
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesviru...
Several viruses interfere with the host immune response by infecting dendritic cells and by altering...
Human herpesvirus 8 (HHV-8) is a recently discovered gammaherpesvirus that is the etiologic agent of...
International audienceBACKGROUND: For an efficient immune response against viral infection, dendriti...
Several lines of evidence suggest that dendritic cells (DCs), the most potent antigen-presenting cel...
Herpesviruses infect most humans. Their infections can be associated with pathological conditions an...
BACKGROUND: Human herpesvirus-8 (HHV-8) is the etiological agent of Kaposi's sarcoma (KS) and of som...
Dissertation presented to obtain the Ph.D degree in BiologyHuman cytomegalovirus (HCMV) is a -herpe...
Human herpesvirus 8 (HHV-8) is a lymphotropic gammaherpesvirus that causes Kaposi's sarcoma (KS), a ...
Evidence indicates that, at least in the early stage, Kaposi's sarcoma (KS) is a cytokine-mediated d...
It is unclear how the immune response controls human herpesvirus 8 (HHV8; also known as Kaposi sarco...
Aim: To evaluate the gene expression changes that occur soon after the active infection of two susce...