MODELLING CELL MIGRATION IN THE MOUSE EMBRYO

The visceral endoderm (VE) is an epithelium of roughly 200 cells encompassing the early mouse embryo. Five and a half We extend previous vertex models by implementing on the surface of an ellipsoid, in order to represent a more realistic geometry for the mouse embryo. days post-fertilisation, a subset of cells at the distal tip of the VE differentiate and migrate towards the boundary between the epiblast and extra-Forces act tangentially to the surface. At each time step, vertex positions ar