Addressing parents’ concerns: do vaccines contain harmful preservatives, adjuvants, additivese, or residuals? Pediatrics. 2003;112 (6 Pt 1):1394–7

ABSTRACT. Vaccines often contain preservatives, ad-juvants, additives, or manufacturing residuals in addi-tion to pathogen-specific immunogens. Some parents, alerted by stories in the news media or information con-tained on the World Wide Web, are concerned that some of the substances contained in vaccines might harm their children. We reviewed data on thimerosal, aluminum, gelatin, human serum albumin, formaldehyde, antibiot-ics, egg proteins, and yeast proteins. Both gelatin and egg proteins are contained in vaccines in quantities sufficient to induce rare instances of severe, immediate-type hyper-sensitivity reactions. However, quantities of mercury, aluminum, formaldehyde, human serum albumin, anti-biotics, and yeast proteins in vaccines have not been found to be harmful in humans or experimental animals. Pediatrics 2003;112:1394–1401; vaccine safety, thimerosal, aluminum, formaldehyde, gelatin, egg proteins, yeast pro-teins