Functional Gene Groupings Activation of NFκB Pathway

The Human NFκB Signaling Pathway RT2 Profiler PCR Array profiles the expression of 84 key genes related to NFκB-mediated signal transduction. The array includes genes that encode members of the Rel, NFκB, and IκB families, NFκB-responsive genes, extracellular ligands and receptors that activate the pathway, and kinases and transcription factors that propagate the signal. NFκB-mediated signal transduction has been implicated in the regulation of viral replication, autoimmune diseases, the inflammatory response, tumorigenesis and apoptosis. Using real-time PCR, you can easily and reliably analyze expression of a focused panel of genes involved in the NFB signal transduction pathway with this array