Add to ORKGIn most cases, the metabolism of drugs leads to pharmacological inactivation through biotransformation to therapeutically inactive molecules. However, drug metabolism can also result in pharmacological activa
Abstract For many years the metabolism of drugs and other xenobiotics was equated with detoxificatio...
Metabolite identification represents a major challenge, and opportunity, for biochemistry. The colle...
In vitro pharmacokinetic data, such as metabolic stability and the identification of formed metaboli...
It has been known for more than 50 years that drugs are not chemically stable compounds providing t...
Drug metabolism as a discipline plays an important role in drug discovery and development and the ef...
In this article, we offer an overview of the compared quantitative importance of biotransformation r...
In this article, we offer an overview of the compared quantitative importance of biotransformation r...
Many drugs are lipid soluble, weak organic acids or bases that are not readily eliminated from the b...
In vitro Biotransformation studies play a crucial role in drug discovery program that determine the ...
Drug metabolism comprises the identification, characterization, and quantification of the chemicals ...
Drug metabolism or more generally, xenobiotic metabolism, is the biotransformation of exogenous comp...
Although bioactivation is a well-documented process and the role of active metabolites in the drug d...
The pharmaceutical industry has significantly contributed to improving human health. Drugs have been...
In the past few decades, drug metabolism research has played an ever increasing role in the design o...
ABSTRACT: The pharmaceutical industry has significantly contributed to improving human health. Drugs...
Abstract For many years the metabolism of drugs and other xenobiotics was equated with detoxificatio...
Metabolite identification represents a major challenge, and opportunity, for biochemistry. The colle...
In vitro pharmacokinetic data, such as metabolic stability and the identification of formed metaboli...
It has been known for more than 50 years that drugs are not chemically stable compounds providing t...
Drug metabolism as a discipline plays an important role in drug discovery and development and the ef...
In this article, we offer an overview of the compared quantitative importance of biotransformation r...
In this article, we offer an overview of the compared quantitative importance of biotransformation r...
Many drugs are lipid soluble, weak organic acids or bases that are not readily eliminated from the b...
In vitro Biotransformation studies play a crucial role in drug discovery program that determine the ...
Drug metabolism comprises the identification, characterization, and quantification of the chemicals ...
Drug metabolism or more generally, xenobiotic metabolism, is the biotransformation of exogenous comp...
Although bioactivation is a well-documented process and the role of active metabolites in the drug d...
The pharmaceutical industry has significantly contributed to improving human health. Drugs have been...
In the past few decades, drug metabolism research has played an ever increasing role in the design o...
ABSTRACT: The pharmaceutical industry has significantly contributed to improving human health. Drugs...
Abstract For many years the metabolism of drugs and other xenobiotics was equated with detoxificatio...
Metabolite identification represents a major challenge, and opportunity, for biochemistry. The colle...
In vitro pharmacokinetic data, such as metabolic stability and the identification of formed metaboli...