Efficacy of intraperitoneal clindamycin in refractory peritonitis-report of two cases. Peritoneal Dialysis Bulletin 4 : 92-94. has a unique property of maintaining squamous epithelial surfaces, as demonstrated by the normal histological appearances of the

Two patients on CAPD developed peritonitis refractory to antibiotics appropriate to the cultured organisms. In one case, cultures remained positive for the offending bacteria (Staphylococcus aureus) and, in the other, cultures of E nterobacter agglomerans rapidly became negative but signs and symptoms of peritonitis per-sisted. Empiric clindamycin therapy was associated with rapid resolution of peritonitis in both instances without necessitating catheter removal. We suggest that, in selected cases of refractory peritonitis, the addition of clindamycin may lead to clearing of the infection with preservation of the peritoneal catheter. Recently Vas (I) reviewed the indications for the removal of permanent peritoneal catheters from patients on chronic peritoneal dialysis. These include persistent exit-site and/or tunnel infections, especially when the same organism is involved in peritonitis, rapidly recurring peritonitis with the same organism implying a tunnel or cuff infection, fungal peritonitis, tuberculous peritonitis, and various mechanical causes leading to catheter malfunction. In addition, peritoniti