Product Ingredients NVP

Background: Generic antiretroviral (ARV) medications have recently become available in many developing countries at costs that are far cheaper than discounted proprietary agents. There are currently no publicly available data describing the integrity (drug content vs. label claim) of these preparations. We analyzed the content of several generic and proprietary ARV formulations containing the non-nucleoside reverse transcriptase inhibitor nevirapine (NVP) as part of a pilot, quality assurance investigation. Methods: Tablets containing NVP (alone or in combination with other ARVs) were obtained from six international sources. NVP content of the six products was determined by HPLC. In total, six chromatographic analyses were performed for each individual tablet. Results: NVP content and demographic data for the individual products are listed in the table