Hindgut, and Unknown Primary

NET liver metastases is heterogeneous including surgi-cal, medical, radiological and nuclear medical possibili-ties; all methods have potential therapeutic benefits and their indications and outcomes are discussed in detail here. The broad range of treatments underlines the need for a multidisciplinary approach in considering therapy for patients with digestive NETs. Epidemiology Endocrine tumors are heterogeneous diseases in terms of both biological features and clinical behavior. One of the major prognostic factors that dramatically affects pa-tient survival is the presence of liver metastases. It has been demonstrated that patients with liver metastases have a worse survival rate when compared to those with-out liver involvement [7–9]. Unfortunately, a large pro