doi: 10.1093/ndt/gfp040 Original Article Glomerular filtration rate and serum phosphate: an inverse

Background. Available data indicate that serum phosphate increases only when glomerular filtration rate (GFR) falls into the low range (<60 mL/min × 1.73 m2). GFR and serum phosphate decrease with ageing. This population-based study investigated by age-controlled analyses the re-lationship ofGFRwith serumphosphate in adults withGFR above the low range. Methods.Datawere collected on age, sex,menstrual status, anthropometry, overnight urinary creatinine, dietary protein (overnight urinary urea), reported intake of milk/yogurt, serum creatinine, phosphate, calcium and total protein in 4034 adults (age 18–91 years) with GFR ≥60 mL/min × 1.73 m2 as assessed by estimated GFR (eGFR, simplified MDRD equation) and creatinine clearance (overnight uri