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ngeles, ruary 2 This review considers the effectiveness of drug dependence treatment in preventing HIV transmission among injecting drug users (IDUs). Substitution programmes using agonist pharmacotherapy (e.g. methadone and buprenorphine maintenance treatment) are available only for drug use (MMT) and decrease in MMT is ass decreases, in HIV prevent HIV risk beh opioid use. T treatment an There is cur substitution been few co treatment fo including s