Case Report Low-Concentration Topical Tacrolimus Ointment in the Treatment of Vulvar Lichen Sclerosus in a Child

Key Words: lichen sclerosus, children, topical tacrolimus Observations: Lichen sclerosus is a chronic inflammatory disease with a predisposition of the ano-genital region. Topical corticosteroid is effective; however, a continuous treatment is often re-quired. After its stoppage the recurrence is often and the side effects of repeated local application of potent glucocorticosteroids may be seen that is why an equally-effective, safer therapeutic op-tions are needed, especially in the treatment of children. Here, we report a case of vulvar lichen sclerosus in a 6-year-old girl refracted to topical steroid. Af-ter 12 weeks of treatment with 0.03 % tacrolimus ointment once daily, the lesions get resolved with-out any side-effects. This is our first case of topical tacrolimus treatment showing a dramatic effect in the treatment of childhood vulvar lichen sclerosus