respond to tumor necrosis factor (TNF) with a respiratory burst (RB) only after adherence to sur-faces coated with extracellular matrix proteins such as fibronectin and fibrinogen (permissive sub-strates) but not with others such as laminin or collagen (nonpermissive substrates). As PMN ad-herence to both types of surfaces is dependent on 2 integrins, we investigated the molecular basis of the different metabolic response to TNF. In partic-ular, we evaluated the relative role of each 2 integrin (L2, M2, and X2) in adherence and O2 production of PMN residing on fibronectin-and laminin-coated surfaces, which were consid-ered as models of permissive and nonpermissive surfaces, respectively. By using chain-specific monoclonal antibodies (mAb)...
Stimulation of adherent human neutrophils (PMN) with tumor necrosis factor (TNF) triggers protein ty...
Human neutrophils were isolated both from peripheral blood (PB) and from aseptic inflammatory exudat...
known to induce inflammatory responses, such as mono-cyte/macrophage adherence, migration, and accum...
Polymorphonuclear leukocytes (PMN) respond to tumor necrosis factor (TNF) with a respiratory burst (...
The production of O2- in response to LPS, PAF, FMLP, TNF and PMA by human neutrophils in suspension ...
The ability of thioglycollate (TG)-elicited mouse peritoneal macrophages to adhere to a laminin subs...
Eosinophils interact with extracellular matrix proteins and endothelial cells through adhesion prote...
We examined whether preincubating polymorphonuclear leukocytes (PMN) with TNFα would result in an en...
We have examined the capacity of four different chemoattractants/cytokines to promote directed migra...
Abstract Background: Migration, production of reactive oxygen species (ROS), release of myeloperoxid...
Abstract: Induction of b1 integrin (CD49/CD29) expression in polymorphonuclear leukocytes (PMN) has ...
Endothelial cells from human umbilical vein (HEC) express several distinct integrin complexes that m...
Macrophages could adhere to extracellular matrix molecules(ECM) to induce the expression of pro-infl...
Macrophages require activation with either PMA (Mercurio, A. M., and L. M. Shaw. 1988. J. Cell Biol....
Tissue injury triggers inflammatory responses that may result in release of degradation products or ...
Stimulation of adherent human neutrophils (PMN) with tumor necrosis factor (TNF) triggers protein ty...
Human neutrophils were isolated both from peripheral blood (PB) and from aseptic inflammatory exudat...
known to induce inflammatory responses, such as mono-cyte/macrophage adherence, migration, and accum...
Polymorphonuclear leukocytes (PMN) respond to tumor necrosis factor (TNF) with a respiratory burst (...
The production of O2- in response to LPS, PAF, FMLP, TNF and PMA by human neutrophils in suspension ...
The ability of thioglycollate (TG)-elicited mouse peritoneal macrophages to adhere to a laminin subs...
Eosinophils interact with extracellular matrix proteins and endothelial cells through adhesion prote...
We examined whether preincubating polymorphonuclear leukocytes (PMN) with TNFα would result in an en...
We have examined the capacity of four different chemoattractants/cytokines to promote directed migra...
Abstract Background: Migration, production of reactive oxygen species (ROS), release of myeloperoxid...
Abstract: Induction of b1 integrin (CD49/CD29) expression in polymorphonuclear leukocytes (PMN) has ...
Endothelial cells from human umbilical vein (HEC) express several distinct integrin complexes that m...
Macrophages could adhere to extracellular matrix molecules(ECM) to induce the expression of pro-infl...
Macrophages require activation with either PMA (Mercurio, A. M., and L. M. Shaw. 1988. J. Cell Biol....
Tissue injury triggers inflammatory responses that may result in release of degradation products or ...
Stimulation of adherent human neutrophils (PMN) with tumor necrosis factor (TNF) triggers protein ty...
Human neutrophils were isolated both from peripheral blood (PB) and from aseptic inflammatory exudat...
known to induce inflammatory responses, such as mono-cyte/macrophage adherence, migration, and accum...