Add to ORKGAIM: To study the effect of IGF-1/IGF-1R and gastrin/ CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS: mRNA expression levels of IGF-1/IGF-1R and gastrin/CCK-BR were assessed by RT-PCR method in gastric cancer tissues, adjacent mucosa, and tumor-free tissues from 56 patients with gastric carcinoma and normal gastric mucosae from 56 healthy controls. Tissue specimens were obtained by biopsy and confirmed by histological evaluation. RESULTS: The mRNA levels of IGF-1/IGF-1R were increased in gastric cancer tissues compared with norma
<p>A) The expression of SP1 increases with tumor progression from precancerous to malignant lesions....
Gastric cancer (GC) is the second leading cause of cancer-related death. The poor survival rate may ...
AIM: The expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt-1 by ...
Background/Aims: Insulin-like growth factor-1 receptor (IGF-1R) plays critical roles in cell prolife...
Gastric cancer (GC) is a heterogeneous disease that is not well detected by current tumor markers. I...
Gastric carcinoma is the fourth most common cause of cancer death worldwide but its molecular biolog...
The purpose of this study was to investigate differential expression of TGF-β1 in gastric tissues re...
1α) is a mediator of tumor progression. Vascular en-dothelial growth factor (VEGF) is the most poten...
Purpose of the study. The purpose of the study was to find the difference between local levels of VE...
Background/Aims: Elevated levels of serum gastrin (SG) have been associated with tumorigenic effects...
between endogenous gene expression and growth regulation induced by TGF-β1 in human gastric cancer c...
Gastric cancer is one of the most severe complex diseases with high morbidity and mortality in the w...
Background/Aims: IGF-1 can act as an endocrine hormone and its signaling server as essential roles i...
AIM: To investigate the expression of 1A6 gene in the lesions during the development of intestinal g...
Objective: The insulin-like growth factor (IGF) system has been known to play a critical role in tum...
<p>A) The expression of SP1 increases with tumor progression from precancerous to malignant lesions....
Gastric cancer (GC) is the second leading cause of cancer-related death. The poor survival rate may ...
AIM: The expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt-1 by ...
Background/Aims: Insulin-like growth factor-1 receptor (IGF-1R) plays critical roles in cell prolife...
Gastric cancer (GC) is a heterogeneous disease that is not well detected by current tumor markers. I...
Gastric carcinoma is the fourth most common cause of cancer death worldwide but its molecular biolog...
The purpose of this study was to investigate differential expression of TGF-β1 in gastric tissues re...
1α) is a mediator of tumor progression. Vascular en-dothelial growth factor (VEGF) is the most poten...
Purpose of the study. The purpose of the study was to find the difference between local levels of VE...
Background/Aims: Elevated levels of serum gastrin (SG) have been associated with tumorigenic effects...
between endogenous gene expression and growth regulation induced by TGF-β1 in human gastric cancer c...
Gastric cancer is one of the most severe complex diseases with high morbidity and mortality in the w...
Background/Aims: IGF-1 can act as an endocrine hormone and its signaling server as essential roles i...
AIM: To investigate the expression of 1A6 gene in the lesions during the development of intestinal g...
Objective: The insulin-like growth factor (IGF) system has been known to play a critical role in tum...
<p>A) The expression of SP1 increases with tumor progression from precancerous to malignant lesions....
Gastric cancer (GC) is the second leading cause of cancer-related death. The poor survival rate may ...
AIM: The expression of vascular endothelial growth factor (VEGF) and its receptors KDR and Flt-1 by ...