RISK ASSESSMENT Development of a Refined Database of Relative Potency Estimates to Facilitate Better Characterization of Variability and Uncertainty in the Current Mammalian TEFs for PCDDs, PCDFs, and Dioxin-like PCBs

The toxic equivalency factor (TEF) approach has been widely accepted as the most feasible and plausible method presently available for evaluating potential health risks associated with exposure to mixtures of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like polychlorinated biphenyls (PCBs)1,2,3,4,5,6. In accordance with thi