2 Centre of Biomedical Engineering Bulgarian Academy of Sciences

Summary: The Cardiac syndrome X includes patients, mainly women, with the triad of angina pectoris, a positive exercise electrocardiogram for myocardial ischemia and angiographically smooth coronary arteries. The most common manifested clinical symptom in those patients is chest pain. In most cases, the syndrome is associated with debilitating symptomology, increased psychological morbidity and a poor quality of life. All the heterogeneity of the syndrome makes the treatment approaches to those patients unclear and uncertain