S-Nitrosocysteine Inhibition of Human Platelet Secretion Is Correlated With Increases in Platelet cGMP Levels

Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels.

Riba, Rocio
Nicolaou, Anna
Troxler, M.
Homer-Vanniasinkam, Shervanthi
Naseem, Khalid M.

January 2004

NoElevated plasma concentrations of the sulphur-containing amino acid homocysteine (Hcy) is associat...

Intraplatelet cyclic 3'-5' guanosine monophosphate is related to serum cholesterol

Anwaar, I.
Gottsäter, A.
Wallmark, A.
Hedblad, B.
Lindgärde, F.
Mattiasson, I.

January 1996

Nitric oxide (NO) exerts its vasodilator and antiaggregatory effects through activation of soluble g...

Hypercysteinemia promotes atherosclerosis by reducing protein S-nitrosylation.

Chen, Yulong
Liu, Ruihan
Zhang, Guangwei
Yu, Qi
Jia, Min
Zheng, Chao
Wang, Yanli
Xu, Cangbao
Zhang, Yaping
Liu, Enqi

January 2015

Protein S-nitrosylation plays important role in the regulation of cardiovascular functions in nitric...

Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets

Tsikas, Dimitrios
Ikic, Milos
Tewes, Kathrin S.
Raida, Manfred
Frölich, Jürgen C.

January 1999

AbstractS-Nitroso-cysteine (SNC), a putative endothelium-derived relaxing factor, potently inhibited...

Homocysteine decreases platelet NO level via protein kinase C activation

Signorello, MARIA GRAZIA
Segantin, A
Passalacqua, Mario
Leoncini, Giuliana

January 2009

Hyperhomocysteinaemia has been associated with increased risk of thrombosis and atherosclerosis. Hom...

An ex vivo standardized assay to measure human platelet cGMP

Bianca RDD
Mitidieri E
Mirone V
Fusco F
Imbimbo C
Cirino G
Sorrentino R

January 2011

Introduction: Nitric oxide (NO) acts a pleiotropic biomodulator in several systems, including the ca...

Effect of homocysteine on the L-arginine/nitric oxide synthase/nitric oxide pathway in human platelets

Li, JX
Zhang, YG
Yao, XH
Zhang, BW
Du, JB
Tang, CS

January 2002

Recent evidence indicates that chronic hyperhomocysteinemia is an independent risk factor for the de...

S-nitrosothiols as selective antithrombotic agents - possible mechanisms

Gordge, M.P.
Xiao, F.
Gordge, M.P.
Xiao, F.

S-nitrosothiols have a number of potential clinical applications, among which their use as antithrom...

Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration

Marcondes, S.
Cardoso, M.H.M.
Antunes, E.
Morganti, R.P.
Thomazzi, S.M.
De Nucci, G.
Lilla, S.
Murad, F.

November 2015

FAPESP – FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe nitric oxide-mediated actions are m...

Suppressed anti-aggregating and cGMP-elevating effects of sodium nitroprusside in platelets from patients with stable angina pectoris

Chirkov, Y.
Chirkova, L.
Horowitz, J.

January 1996

Platelet hyperactivity plays an important role in the pathogenesis of cardio-vascular diseases. In p...

Lack of correlation between the observed stability and pharmacological properties of S-nitroso derivatives of glutathione and cysteine-related peptides

Tullett, Jayne M.
Rees, Daryl D.
Shuker, David E. G.
Gescher, Andreas

November 2001

S-Nitrosothiols (RSNOs) have been widely studied as donors of nitric oxide. In general, RSNOs are co...

Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway

Topf, Hans-Georg
Rauh, Manfred
Rascher, Wolfgang
Dötsch, Jörg
Klinge, Jens M.

January 2013

The clinical use of Sodium nitroprusside (SNP) may be associated with an alteration of platelet func...

Specific transport of S-nitrosocysteine in human red blood cells: Implications for formation of S-nitrosothiols and transport of NO bioactivity within the vasculature

Sandmann, Jörg
Schwedhelm, Kathrin S.
Tsikas, Dimitrios

August 2005

AbstractThe transport of various S-nitrosothiols, NO and NO donors in human red blood cells (RBC) an...

Comprehensive identification of nitroxyl-reactive cysteines in human platelet proteins by quantitative mass spectrometry

Lin, Liwen

November 2011

HNO, a small compound which can be produced upon hydrolysis of Angeli’s Salt, is known to be able to...

Globular adiponectin increases cGMP formation in blood platelets independently of nitric oxide

Naseem, Khalid M.
Aburima, Ahmed
Riba, R.
Patel, B.
Aburima, A.
Naseem, K. M.

October 2008

Background: Platelet-derived nitric oxide (NO) has been shown to play conflicting roles in platelet ...

Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels.

Riba, Rocio
Nicolaou, Anna
Troxler, M.
Homer-Vanniasinkam, Shervanthi
Naseem, Khalid M.

January 2004

NoElevated plasma concentrations of the sulphur-containing amino acid homocysteine (Hcy) is associat...

Intraplatelet cyclic 3'-5' guanosine monophosphate is related to serum cholesterol

Anwaar, I.
Gottsäter, A.
Wallmark, A.
Hedblad, B.
Lindgärde, F.
Mattiasson, I.

January 1996

Nitric oxide (NO) exerts its vasodilator and antiaggregatory effects through activation of soluble g...

Hypercysteinemia promotes atherosclerosis by reducing protein S-nitrosylation.

Chen, Yulong
Liu, Ruihan
Zhang, Guangwei
Yu, Qi
Jia, Min
Zheng, Chao
Wang, Yanli
Xu, Cangbao
Zhang, Yaping
Liu, Enqi

January 2015

Protein S-nitrosylation plays important role in the regulation of cardiovascular functions in nitric...

Inhibition of platelet aggregation by S-nitroso-cysteine via cGMP-independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets

Tsikas, Dimitrios
Ikic, Milos
Tewes, Kathrin S.
Raida, Manfred
Frölich, Jürgen C.

January 1999

AbstractS-Nitroso-cysteine (SNC), a putative endothelium-derived relaxing factor, potently inhibited...

Homocysteine decreases platelet NO level via protein kinase C activation

Signorello, MARIA GRAZIA
Segantin, A
Passalacqua, Mario
Leoncini, Giuliana

January 2009

Hyperhomocysteinaemia has been associated with increased risk of thrombosis and atherosclerosis. Hom...

An ex vivo standardized assay to measure human platelet cGMP

Bianca RDD
Mitidieri E
Mirone V
Fusco F
Imbimbo C
Cirino G
Sorrentino R

January 2011

Introduction: Nitric oxide (NO) acts a pleiotropic biomodulator in several systems, including the ca...

Effect of homocysteine on the L-arginine/nitric oxide synthase/nitric oxide pathway in human platelets

Li, JX
Zhang, YG
Yao, XH
Zhang, BW
Du, JB
Tang, CS

January 2002

Recent evidence indicates that chronic hyperhomocysteinemia is an independent risk factor for the de...

S-nitrosothiols as selective antithrombotic agents - possible mechanisms

Gordge, M.P.
Xiao, F.
Gordge, M.P.
Xiao, F.

S-nitrosothiols have a number of potential clinical applications, among which their use as antithrom...

Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration

Marcondes, S.
Cardoso, M.H.M.
Antunes, E.
Morganti, R.P.
Thomazzi, S.M.
De Nucci, G.
Lilla, S.
Murad, F.

November 2015

FAPESP – FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe nitric oxide-mediated actions are m...

Suppressed anti-aggregating and cGMP-elevating effects of sodium nitroprusside in platelets from patients with stable angina pectoris

Chirkov, Y.
Chirkova, L.
Horowitz, J.

January 1996

Platelet hyperactivity plays an important role in the pathogenesis of cardio-vascular diseases. In p...

Lack of correlation between the observed stability and pharmacological properties of S-nitroso derivatives of glutathione and cysteine-related peptides

Tullett, Jayne M.
Rees, Daryl D.
Shuker, David E. G.
Gescher, Andreas

November 2001

S-Nitrosothiols (RSNOs) have been widely studied as donors of nitric oxide. In general, RSNOs are co...

Endothelial cells influence the sodium nitroprusside mediated inhibition of platelet aggregation by an as yet unkown pathway

Topf, Hans-Georg
Rauh, Manfred
Rascher, Wolfgang
Dötsch, Jörg
Klinge, Jens M.

January 2013

The clinical use of Sodium nitroprusside (SNP) may be associated with an alteration of platelet func...

Specific transport of S-nitrosocysteine in human red blood cells: Implications for formation of S-nitrosothiols and transport of NO bioactivity within the vasculature

Sandmann, Jörg
Schwedhelm, Kathrin S.
Tsikas, Dimitrios

August 2005

AbstractThe transport of various S-nitrosothiols, NO and NO donors in human red blood cells (RBC) an...

Comprehensive identification of nitroxyl-reactive cysteines in human platelet proteins by quantitative mass spectrometry

Lin, Liwen

November 2011

HNO, a small compound which can be produced upon hydrolysis of Angeli’s Salt, is known to be able to...

Globular adiponectin increases cGMP formation in blood platelets independently of nitric oxide

Naseem, Khalid M.
Aburima, Ahmed
Riba, R.
Patel, B.
Aburima, A.
Naseem, K. M.

October 2008

Background: Platelet-derived nitric oxide (NO) has been shown to play conflicting roles in platelet ...

Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels.

Riba, Rocio
Nicolaou, Anna
Troxler, M.
Homer-Vanniasinkam, Shervanthi
Naseem, Khalid M.

January 2004

NoElevated plasma concentrations of the sulphur-containing amino acid homocysteine (Hcy) is associat...

Intraplatelet cyclic 3'-5' guanosine monophosphate is related to serum cholesterol

Anwaar, I.
Gottsäter, A.
Wallmark, A.
Hedblad, B.
Lindgärde, F.
Mattiasson, I.

January 1996

Nitric oxide (NO) exerts its vasodilator and antiaggregatory effects through activation of soluble g...

Hypercysteinemia promotes atherosclerosis by reducing protein S-nitrosylation.

Chen, Yulong
Liu, Ruihan
Zhang, Guangwei
Yu, Qi
Jia, Min
Zheng, Chao
Wang, Yanli
Xu, Cangbao
Zhang, Yaping
Liu, Enqi

January 2015

Protein S-nitrosylation plays important role in the regulation of cardiovascular functions in nitric...

S-Nitrosocysteine Inhibition of Human Platelet Secretion Is Correlated With Increases in Platelet cGMP Levels

Abstract

Extracted data

S-Nitrosocysteine Inhibition of Human Platelet Secretion Is Correlated With Increases in Platelet cGMP Levels

Abstract

Extracted data

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