Prostate Randomized controlled trial Review Saline

prostate Context: Incorporation of bipolar technology in transurethral resection (TUR) of the pros-tate (TURP) potentially offers advantages over monopolar TURP (M-TURP). Objective: To evaluate the evidence by a meta-analysis, based on randomized controlled trials (RCTs) comparing bipolar TURP (B-TURP) with M-TURP for benign prostatic obstruc-tion. Primary end points included efficacy (maximum flow rate [Qmax], International Prostate Symptom Score) and safety (adverse events). Secondary end points included operation time and duration of irrigation, catheterization, and hospitalization. Evidence acquisition: Based on a detailed, unrestricted strategy, the literature was searched up to February 19, 2009, using Medline, Embase, Science Citation Index, and the Cochrane Library to detect all relevant RCTs. Methodological quality assessment of the trials was based on the Dutch Cochrane Collaboration checklist. Meta-analysis was performed using Review Manager 5.0. Evidence synthesis: Sixteen RCTs (1406 patients) were included. Overall trial quality wa