Metabolic Control Response to Weight Reduction in Obese Non-Insulin Dependent Diabetic Patients

Abstract: Obesity is common in non-insulin dependent diabetic patients and weight loss produces a significant health gains. The aim of this study was to determine the metabolic response following weight reduction in obese non insulin dependent diabetic patients. Forty obese non-insulin dependent diabetics participated in this study and divided into two equal groups; the first group (A) received physical training combined with dietary measures and medical treatment. The second group (B) received only medical treatment and no physical therapy intervention. The program consisted of three sessions per week for three months. There was a significant increase in glcocylated hemoglobin (HBA c) and decrease in Body Mass Index (BMI) and leptin of group (A),1 while the results of group (B) were not significant. There was a significant difference between both groups. There was a strong direct relationship between the leptin, HBA c and BMI in both groups. So, weight reduction1 via physical training and diet regimen is an effective treatment policy to improve the metabolic control in obese diabetic patients