Add to ORKGIntroduction to the pharmacological design The effects of PGs and LTs in the physiopathology of inflammation are well known. However, the role of arachidonic acid (AA) metabolites in pathologies other than inflammation, such as cancer, has only recently been described. Hong et al. [1] demonstrated that COX-1 and 5-LOX were universally expressed in all cancer cel
Purpose: The arachidonic acid pathway incorporates phospholipase, cyclooxygenase, lipoxygenase and e...
Regulation of Cytokinetics of the HT-29 human colorectal cancer cells and its interactions with TNF-...
Cyclooxygenase (COX) inhibitors are being developed as potential agents for the prevention and treat...
Cancer and inflammation are intimately linked due to specific oxidative processes in the tumor micro...
Arachidonic acid (AA) metabolism is a critical process mediated by a number of enzymes that control ...
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes...
Prostaglandins and thromboxane are lipid signaling molecules deriving from arachidonic acid by the a...
Arachidonic acid (AA) and its metabolites have recently generated a heightened interest due to growi...
two key enzymes that play important roles in the metab-olism of arachidonic acid (AA) to pro-inflamm...
<p>ARA is metabolized by three enzyme families, cyclooxygenase (COX), lipoxygenase (LOX), and cytoch...
Drug molecules not only interact with specific targets, but also alter the state and function of the...
Emerging on the horizon in cancer therapy is an expansion of the scope of treatment beyond cytotoxic...
Cellular levels of free arachidonic acid (AA) are tightly controlled through enzymatic release of th...
dissertationThis dissertation describes the modification and inactivation of tumor suppressors by ar...
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes...
Purpose: The arachidonic acid pathway incorporates phospholipase, cyclooxygenase, lipoxygenase and e...
Regulation of Cytokinetics of the HT-29 human colorectal cancer cells and its interactions with TNF-...
Cyclooxygenase (COX) inhibitors are being developed as potential agents for the prevention and treat...
Cancer and inflammation are intimately linked due to specific oxidative processes in the tumor micro...
Arachidonic acid (AA) metabolism is a critical process mediated by a number of enzymes that control ...
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes...
Prostaglandins and thromboxane are lipid signaling molecules deriving from arachidonic acid by the a...
Arachidonic acid (AA) and its metabolites have recently generated a heightened interest due to growi...
two key enzymes that play important roles in the metab-olism of arachidonic acid (AA) to pro-inflamm...
<p>ARA is metabolized by three enzyme families, cyclooxygenase (COX), lipoxygenase (LOX), and cytoch...
Drug molecules not only interact with specific targets, but also alter the state and function of the...
Emerging on the horizon in cancer therapy is an expansion of the scope of treatment beyond cytotoxic...
Cellular levels of free arachidonic acid (AA) are tightly controlled through enzymatic release of th...
dissertationThis dissertation describes the modification and inactivation of tumor suppressors by ar...
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes...
Purpose: The arachidonic acid pathway incorporates phospholipase, cyclooxygenase, lipoxygenase and e...
Regulation of Cytokinetics of the HT-29 human colorectal cancer cells and its interactions with TNF-...
Cyclooxygenase (COX) inhibitors are being developed as potential agents for the prevention and treat...