Microsatellite Instability Analysis with GeneMarker®

Microsatellites are stretches of DNA where a 1-5 base pair sequence is repeated several times. The most common microsatellite in the humans is a dinucleotide repeat of CA which occurs tens of thousands of times across the genome. Microsatellite instability (MSI) is a condition where repeat units are gained or lost within a locus resulting in length polymorphism. Certain repeat regions are known to be highly polymorphic and hereditable. In the forensics community, these sites are useful when identifying markers for DNA fingerprinting. Conversely, microsatellite instability within and aroun