Effects of Concentration and Temperature on the Stabil- ity of Nevirapine in Whole Blood and Serum, Chantelle J.

resource-poor regions of the world, the antiretroviral nonnucleoside reverse transcriptase inhibitor nevirapine (NVP) is widely prescribed for HIV treatment and pre-vention because of its relative safety, long half-life, and low cost. Furthermore, pregnant women are often pre-scribed NVP therapy to decrease the rate of mother-to-child HIV transmission or as part of a combination therapeutic regimen in more developed countries. As one example, measuring NVP concentrations in pregnant women and their infants, in particular, has increased as clinics in developing countries attempt to better assess NVP “coverage ” (e.g., universal treatment regardless of HIV status vs targeted treatment) (1). Because most developing countries currently do not have state-of-the-art sample collection, processing, and/or storage capabil