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Canada consistently receives more than 239 000 immi-grants yearly, up to 35 000 of whom are refugees.1Many arrive with similar or better self-reported health than the general Canadian population reports, a phenomenon described as the “healthy immigrant effect.”2–6 However, sub-groups of immigrants, for example refugees, face health dis-parities and often a greater burden of infectious diseases.7,8 These health issues sometimes differ from the general popula-tion because of differing disease exposures, vulnerabilities, social determinants of health and access to health services before, during and after migration. Cultural and linguistic dif-ferences combined with lack of evidence-based guidelines can contribute to poor delivery of services.9,10 Community-based primary health care practitioners see most of the immigrants and refugees who arrive in Canada. This is not only because Canada’s health system centres on pri-mary care practice, but also because people with lower socio-economic status, language barriers and less familiarity with the system are much less likely to receive specialist care.11 Guideline development can be costly in terms of time, resources and expertise.12 Setting priorities is critical, particu-larly when dealing with complex situations and limited resources.13 There is no standard algorithm on who should and how they should determine top priorities for guidelines, although burden of illness, feasibility and economic considera-tions are all important.14 Stakeholder engagement to ensure rel-evance and acceptability, and the use of an explicit procedure for developing recommendations are critical in guideline development.15–17 We chose primary care practitioners, particu-larly those who care for immigrants and refugees, to help the guideline committee select conditions for clinical preventiv