Crystallins, the structural proteins of the lens, have been isolated from human lenses using a combination of gel filtration and reversed phase high performance liquid chromatography (HPLC). The molecular weights of the isolated crystallins have been determined by electrospray ionization mass spectrometry. The isolated crystallins have also been proteolytically digested into peptides, the peptides fractionated by HPLC, and the masses of the peptides determined by fast atom bombardment mass spectrometry. With these techniques, it is possible to confirm and/or correct known protein sequences and identify and locate post translational modifications
Age-related protein truncation is a common process in long-lived proteins such as proteins found in ...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...
Cataract, an opacity of the lens, is the major cause of blindness worldwide. Lens α-crystallins are ...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
Mammalian lenses, including human and bovine, contain three major classes of soluble lens proteins α...
Low molecular weight peptides derived from the breakdown of crystallins have been reported in adult ...
Human lens proteins from clear lenses were separated and identified using two-dimensional polyacryla...
The major function of human lens is to focus the incident light on the retina without light scatteri...
The major function of human lens is to focus the incident light on the retina without light scatteri...
The lens is an ideal tissue to study growth and ageing since it continually grows throughout life ac...
One of the low molecular weight proteins of bovine lens extract, designated as βs-crystallin, was pu...
One of the low molecular weight proteins of bovine lens extract, designated as βs-crystallin, was pu...
Age-related protein truncation is a common process in long-lived proteins such as proteins found in ...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...
Cataract, an opacity of the lens, is the major cause of blindness worldwide. Lens α-crystallins are ...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-tr...
Mammalian lenses, including human and bovine, contain three major classes of soluble lens proteins α...
Low molecular weight peptides derived from the breakdown of crystallins have been reported in adult ...
Human lens proteins from clear lenses were separated and identified using two-dimensional polyacryla...
The major function of human lens is to focus the incident light on the retina without light scatteri...
The major function of human lens is to focus the incident light on the retina without light scatteri...
The lens is an ideal tissue to study growth and ageing since it continually grows throughout life ac...
One of the low molecular weight proteins of bovine lens extract, designated as βs-crystallin, was pu...
One of the low molecular weight proteins of bovine lens extract, designated as βs-crystallin, was pu...
Age-related protein truncation is a common process in long-lived proteins such as proteins found in ...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...
Four low molecular weight proteins, designated as β2-, γ0-, γ1- and γ2-crystallin, have been isolate...