Summary. The 4-quinolone PD127,391 displays a biphasic effect on Escherichia coli, Staphylococcus aureus and S. epidermidis in nutrient broth. It is as active as ciprofloxacin in terms of its optimum bactericidal concentration against E. coli. However, against staphylococci it is six times as active as ciprofloxacin or any other 4-quinolone previously investigated. Although protein and RNA synthesis are not required for bactericidal activity, cell division is essential
anaerobes. antimicrobials against clinically important 12-8039, a new quinolone, and other Compariso...
BMS-284756 (T-3811) is a novel quinolone that lacks a flu-orine at the C-6 position. BMS-284756 has ...
The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spec...
In vitro activities of LB20304a were compared with those of grepafloxacin (OPC-17116), Q-35, ciprofl...
PD 138312 and PD 140248 are new quinolones with high in vitro activities against a wide spectrum of ...
The in-vitro activity of PD 117558, a new quinolone antimicrobial agent, was compared to that of fou...
The in vitro activities of three new quinolones (sparfloxacin, CI-960, and PD 131,628) were compared...
DW-224a showed the most potent in vitro activity among the quinolone compounds tested against clinic...
NM394 is a new 6-fluoroquinolone antibacterial agent with a tricyclic structure which has a bridge t...
The in-vitro activities of CI-934 and other commonly used antibiotics were determined against 598 cl...
The in vitro antibacterial activity of NM394 was compared with those of other new quinolones. NM394 ...
quinolones are broad-spectrum antibacterial agents.they have many clinical uses which are increasing...
The accumulation of quinolones by Escherichia coli JF568, Pseudomonas aeruginosa PAO1, and Staphylo-...
The in-vitro activity of Bay y 3118, a new quinolone antimicrobial was compared with that of ciprofl...
E-5065, and E-5068) against 100 Bacteroides fragilis group bacterial isolates were compared with tho...
anaerobes. antimicrobials against clinically important 12-8039, a new quinolone, and other Compariso...
BMS-284756 (T-3811) is a novel quinolone that lacks a flu-orine at the C-6 position. BMS-284756 has ...
The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spec...
In vitro activities of LB20304a were compared with those of grepafloxacin (OPC-17116), Q-35, ciprofl...
PD 138312 and PD 140248 are new quinolones with high in vitro activities against a wide spectrum of ...
The in-vitro activity of PD 117558, a new quinolone antimicrobial agent, was compared to that of fou...
The in vitro activities of three new quinolones (sparfloxacin, CI-960, and PD 131,628) were compared...
DW-224a showed the most potent in vitro activity among the quinolone compounds tested against clinic...
NM394 is a new 6-fluoroquinolone antibacterial agent with a tricyclic structure which has a bridge t...
The in-vitro activities of CI-934 and other commonly used antibiotics were determined against 598 cl...
The in vitro antibacterial activity of NM394 was compared with those of other new quinolones. NM394 ...
quinolones are broad-spectrum antibacterial agents.they have many clinical uses which are increasing...
The accumulation of quinolones by Escherichia coli JF568, Pseudomonas aeruginosa PAO1, and Staphylo-...
The in-vitro activity of Bay y 3118, a new quinolone antimicrobial was compared with that of ciprofl...
E-5065, and E-5068) against 100 Bacteroides fragilis group bacterial isolates were compared with tho...
anaerobes. antimicrobials against clinically important 12-8039, a new quinolone, and other Compariso...
BMS-284756 (T-3811) is a novel quinolone that lacks a flu-orine at the C-6 position. BMS-284756 has ...
The quinolone antibiotics arose in the early 1960s, with the first examples possessing a narrow-spec...
DOI
Add to ORKG