The transcription factor Prox1 is the master regulator of lymphatic endothelial cell differentiation and its expression initiates the morphogenesis of the lymphatic vasculature in the early embryo. Two new studies now answer some fundamental questions concerning Prox1 biology
Background: The PROX1 gene is specifically expressed in a subpopulation of endothelial cells that, b...
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nod...
Despite its essential roles in development and disease, the lymphatic vascular system has been less ...
The process of angiogenesis has been well documented, but little is known about the biology of lymph...
Abstract Background In vivo studies demonstrate that ...
More than 100 years ago, Florence Sabin suggested that lymphatic vessels develop by sprouting from p...
BACKGROUND: In vivo studies demonstrate that the Prox1 transcription factor plays a critical role in...
Detection of lymphatic endothelal cells (LECs) has been problematic because of the lack of specific ...
The lymphatic system plays a key role in tissue fluid regulation and tumour metastasis, and lymphati...
AbstractThe lack of specific markers has raised problems in documenting the precise manner by which ...
In mammals, the homeodomain transcription factor Prox1 acts as the central regulator of lymphatic ce...
Blood vessels and lymphatic vessels are functionally and molecularly distinct. Blood vessels carry r...
AbstractThe homeobox transcription factor PROX1 is essential for the development and maintenance of ...
The specification of arterial, venous, and lymphatic endothelial cell fate is critical during vascul...
The study of lymphatic vessels and lymphatic tumors has been hampered with difficulty due to the ove...
Background: The PROX1 gene is specifically expressed in a subpopulation of endothelial cells that, b...
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nod...
Despite its essential roles in development and disease, the lymphatic vascular system has been less ...
The process of angiogenesis has been well documented, but little is known about the biology of lymph...
Abstract Background In vivo studies demonstrate that ...
More than 100 years ago, Florence Sabin suggested that lymphatic vessels develop by sprouting from p...
BACKGROUND: In vivo studies demonstrate that the Prox1 transcription factor plays a critical role in...
Detection of lymphatic endothelal cells (LECs) has been problematic because of the lack of specific ...
The lymphatic system plays a key role in tissue fluid regulation and tumour metastasis, and lymphati...
AbstractThe lack of specific markers has raised problems in documenting the precise manner by which ...
In mammals, the homeodomain transcription factor Prox1 acts as the central regulator of lymphatic ce...
Blood vessels and lymphatic vessels are functionally and molecularly distinct. Blood vessels carry r...
AbstractThe homeobox transcription factor PROX1 is essential for the development and maintenance of ...
The specification of arterial, venous, and lymphatic endothelial cell fate is critical during vascul...
The study of lymphatic vessels and lymphatic tumors has been hampered with difficulty due to the ove...
Background: The PROX1 gene is specifically expressed in a subpopulation of endothelial cells that, b...
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nod...
Despite its essential roles in development and disease, the lymphatic vascular system has been less ...