Infectious disease

Infectious diseaseclosely related to T. pallidum subsp. pallidum and, although they produce different clinical manifestations, infections caused by these organisms are serologically indistinguishable from syphilis. Non-pathogenic treponemes also inhabit the human oral cavity. In-vitro culture of T. pallidum has not been achieved, making study of the organism difficult. Only animal models in which testes of virgin New Zealand white rabbits have been inoculated have made studies of pathogenesi