metabolic control

Macedonia SUMMARY The aim of this study was to analyze and evaluate the efficacy and safety of continuous subcutaneous insulin infusion (CSII) in all patients with type 1 diabetes on pump therapy in Macedonia. The study was performed at University Department of Endocrinology in Skopje from January 2004 until December 2006. CSII was initiated in diabetics with poor metabolic control. HbA1c, severe hypoglycemia and diabetic ketoacidosis in the year before CSII were compared with the respective values during one-year pump treatment. Fourteen patients (6 male and 8 female) aged 18.9±6.4 years with type 1 diabetes were included in the study. The mean HbA1c of 9.4±1.1 % in one year pre-pump period decreased to 7.3±0.8 % one year after CSII. The rate of severe hypoglycemia and diabetic ketoacidosis was reduced upon switch to pump treatment in the next year. CSII is effective and safe treatment in patients with type 1 diabetes to achieve satisfactory metabolic control. Efforts should be invested by healthcare providers to promote this promising alternative treatment in type 1 diabetes