Cancer Aid

uni-regensburg.de doi: 10.1111/j.1755-148X.2010.00684.x Dear Sir, Today’s basic research on cancer is not imaginable without cell culture models, which are indispensable for the definition of molecular processes, for comparison of pathophysiological phenotypes, for studying drug sensi-tivity or the mode of drug action etc. Malignant melanoma is the tumor with the highest number of available cell lines, which sum up to several hundreds (Herlyn, 2008), whereas the research of other tumor entities is often based on an only limited number of cell culture models. While the investigation of a larger num-ber of cell lines increases the likelihood to better cap-ture the biological variation representative for huma