SUMMARY. A simple, rapid, sensitive and selective method of high-performance liquid chromatography with fluorescence detection was developed for determination of puerarin in rat plasma. Chromatography was carried out on a reversed-phase Hypersil ODS column at 30 °C using a mobile phase consisting of methanol- 50 mM NH4OAc in water (23:77, v/v) with a flow rate of 1 mL/min. The excitation wavelength and emission wavelength were 250nm and 480nm, respectively, PMT-gain was set at 11. The method was demonstrated to be selective and sensitive, and a good linear response was observed over a range of 0.16–120.00 μg/mL in rat plasma. The validated method was successfully applied to the characterization of the pharmacokinetics of puerarin in rat pla...
Copyright © 2013 Junbo Xing et al. This is an open access article distributed under the Creative Com...
A specific, sensitive, and reliable high performance liquid chromatography with fluorescence detecti...
A simple, fast and sensitive high performance liquid chromatography-tandem mass spectrometry (HPLC–M...
A simple, rapid, sensitive and selective method of high-performance liquid chromatography with fluor...
Puerarin (PUE) is a compound isolated from the roots of Pueraria lobata. We studied the pharmacokine...
Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biolo...
A pharmacokinetic comparison was made to evaluate the influence from other components in the Radix P...
Abstract Background Pueraria candollei var. mirifica is a medicinal plant that is promoted as a “Cha...
Cheng-Feng Luo,1,2 Ning Hou,2,3 Juan Tian,1,2 Mu Yuan,2,3 Shi-Ming Liu,1,2 Long-Gen Xiong,1,2 Jian-D...
A high performance liquid chromatographic method was developed and applied to the simultaneous deter...
A high performance liquid chromatographic method was developed and applied to the simultaneous deter...
Puerarin is an isoflavonoid extracted from Pueraria lobata roots, and displays a broad range of phar...
<p>Puerarin is a phytochemical with various pharmacological effects, but poor water solubility and l...
The phytoestrogen puerarin has been shown to protect neurons and astrocytes in the brain, and is the...
A liquid chromatograph/mass spectrometry (LC/MS) method was developed for the simultaneous quantitat...
Copyright © 2013 Junbo Xing et al. This is an open access article distributed under the Creative Com...
A specific, sensitive, and reliable high performance liquid chromatography with fluorescence detecti...
A simple, fast and sensitive high performance liquid chromatography-tandem mass spectrometry (HPLC–M...
A simple, rapid, sensitive and selective method of high-performance liquid chromatography with fluor...
Puerarin (PUE) is a compound isolated from the roots of Pueraria lobata. We studied the pharmacokine...
Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biolo...
A pharmacokinetic comparison was made to evaluate the influence from other components in the Radix P...
Abstract Background Pueraria candollei var. mirifica is a medicinal plant that is promoted as a “Cha...
Cheng-Feng Luo,1,2 Ning Hou,2,3 Juan Tian,1,2 Mu Yuan,2,3 Shi-Ming Liu,1,2 Long-Gen Xiong,1,2 Jian-D...
A high performance liquid chromatographic method was developed and applied to the simultaneous deter...
A high performance liquid chromatographic method was developed and applied to the simultaneous deter...
Puerarin is an isoflavonoid extracted from Pueraria lobata roots, and displays a broad range of phar...
<p>Puerarin is a phytochemical with various pharmacological effects, but poor water solubility and l...
The phytoestrogen puerarin has been shown to protect neurons and astrocytes in the brain, and is the...
A liquid chromatograph/mass spectrometry (LC/MS) method was developed for the simultaneous quantitat...
Copyright © 2013 Junbo Xing et al. This is an open access article distributed under the Creative Com...
A specific, sensitive, and reliable high performance liquid chromatography with fluorescence detecti...
A simple, fast and sensitive high performance liquid chromatography-tandem mass spectrometry (HPLC–M...