Benchmarks Single nucleotide polymorphism

(SNP) is the most common variation of the human genome with more than 9 million reported in public databases (1,2). Extensive studies are being made to characterize single SNPs, or haplotypes containing multiple SNPs, which can be used as prognostic and predictive disease markers or as tools to locate new disease genes. A number of techniques to establish the genotype of a known SNP are available, as reviewed in Reference 3. The choice of methodology is dependent on available technology platforms and whether the analysi