Add to ORKGABSTRACT: In situ suppression hybridization with recombinant bacteriophage DNA libraries for chro-mosomes 8 and 21 was performed in two cases of acute nonlymphocytic leukemia, type FAB M2. In both cases, cytogenetic analysis by conventional G-banding revealed t(8;21)(q22;q22J. In situ suppression hybridization was able to prove the reciprocal nature of the translocation in both cases by identifying the terminal end of chromosome 21 translocated to the derivative chromosome 8q-
textabstractSpecific chromosomal translocations are one of the defects associated with leukemia. Iso...
A 39-year-old man was diagnosed as having acute myeloblastic leukemia with maturation (AML-M2). Cyto...
Chromosomal region 11q23 participates in a number of reciprocal translocations with specific regions...
In situ suppression hybridization with recombinant bacteriophage DNA libraries for chromosomes 8 and...
In the translocation (8;21)(q22;q22) associated with acute myelogenous leukemia (AML), part of the l...
Fluorescence In Situ Hybridization (FISH) studies with chromosome-specific libraries and repetitive ...
We describe two novel chromosomal translocations in two cases of leukemia in which these translocati...
The t(8;21)(q22;q22) is a nonrandom translocation specifically marking blasts of acute myelogenous l...
The AMLl gene was rearranged in leukemic cells with t(8;21)(q22;q22) or its variant, complex t(8;V;2...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The t(8;21)(q22;q22) is one of the most frequent chromosomal abnormality associated with acute myelo...
A 43-year-old man was diagnosed with acute myelocytic leukemia with cellular maturation (AML-M2, acc...
We report on a patient with chronic myeloid leukemia (CML), which was detected by conventional cytog...
The translocation (8;21) is a chromosome abnormality associated with acute myeloid leukemia (AML). A...
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted huma...
textabstractSpecific chromosomal translocations are one of the defects associated with leukemia. Iso...
A 39-year-old man was diagnosed as having acute myeloblastic leukemia with maturation (AML-M2). Cyto...
Chromosomal region 11q23 participates in a number of reciprocal translocations with specific regions...
In situ suppression hybridization with recombinant bacteriophage DNA libraries for chromosomes 8 and...
In the translocation (8;21)(q22;q22) associated with acute myelogenous leukemia (AML), part of the l...
Fluorescence In Situ Hybridization (FISH) studies with chromosome-specific libraries and repetitive ...
We describe two novel chromosomal translocations in two cases of leukemia in which these translocati...
The t(8;21)(q22;q22) is a nonrandom translocation specifically marking blasts of acute myelogenous l...
The AMLl gene was rearranged in leukemic cells with t(8;21)(q22;q22) or its variant, complex t(8;V;2...
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
The t(8;21)(q22;q22) is one of the most frequent chromosomal abnormality associated with acute myelo...
A 43-year-old man was diagnosed with acute myelocytic leukemia with cellular maturation (AML-M2, acc...
We report on a patient with chronic myeloid leukemia (CML), which was detected by conventional cytog...
The translocation (8;21) is a chromosome abnormality associated with acute myeloid leukemia (AML). A...
Chromosomal in situ suppression (CISS) hybridization was performed with library DNA from sorted huma...
textabstractSpecific chromosomal translocations are one of the defects associated with leukemia. Iso...
A 39-year-old man was diagnosed as having acute myeloblastic leukemia with maturation (AML-M2). Cyto...
Chromosomal region 11q23 participates in a number of reciprocal translocations with specific regions...