ARTICLE Pregnancy Outcomes in Female Childhood and Adolescent Cancer Survivors A Linked Cancer-Birth Registry Analysis

Objective: To compare birth outcomes among female survivors of childhood and adolescent cancer who sub-sequently bear children, relative to those of womenwith-out a history of cancer. Design: Retrospective cohort study. Setting: Four US regions. Participants:Cancer registries identified girls younger than 20 years whowere diagnosed as having cancer from 1973 through 2000. Linked birth records identified the first live births after diagnosis (n=1898).Comparison sub-jects were selected from birth records (n=14 278). Sur-vivors of genital tract carcinomas underwent separate analysis. Main Exposure: Cancer diagnosis at younger than 20 years