Objective: This study was conducted to study the role of combination therapy of growth hormone and Gonadotropin-releasing hormone (GnRH) analogues in girls with idiopathic central precocious puberty (CPP) or idiopathic short stature (ISS). Methods: Five girls with CPP (median age 9.1 y, pubertal stage 2-3) (3 of them previously treated with GnRH analogue (GnRHa) for 16.2 ± 0.3 months) and 8 girls with ISS (median age 11.4 y, pubertal stage 2-3) (previously treated with GH for 10.95 ± 1.42 months), were treated with recombinant human GH (0.33mg/kg/week) and GnRHa (3.75 mg/28 days) for 22 months. Results: Height of girls with CPP improved from –1.3 to –0.2 SDS and height for BA from –2.1 to –0.6 SDS (P = 0.042). Predicted adult height (PAH) i...
Background: Girls adopted from developing countries often have early or precocious puberty, requirin...
Context: Isolated heterozygous SHOX defects are the most frequent monogenic cause of short stature, ...
Object To study the outcomes of GnRHa on final adult height in Chinese idiopathic central precocious...
OBJECTIVE:Gonadotropin-releasing hormone agonists (GnRHa) are the treatment of choice for central pr...
Objectives: To study the effect of gonadotropin-releasing hormone analogue (GnRHa) on final adult he...
Context: GH treatment is effective in improving height in short children born small for gestational ...
Context:GH treatment is effective in improving height in short children born small for gestational a...
Context: GH treatment is effective in improving height in short children born small for gestational ...
Objective: We assessed in a retrospective unicenter study the impact of treatment with GnRH analogs ...
BACKGROUND/PURPOSE: It has been reported that gonadotropin releasing hormone analogue (GnRHa) therap...
Objective: To assess the long-term effect of prepubertal high-dose GH treatment on growth in childre...
To assess whether delaying puberty may improve final height in GH-deficient children with a poor hei...
It has been reported that gonadotropin releasing hormone analogue (GnRHa) therapy can improve the ad...
Background/PurposeIt has been reported that gonadotropin releasing hormone analogue (GnRHa) therapy ...
Context: Several factors can affect adult height (AH) of patients with gonadotropin-dependent precoc...
Background: Girls adopted from developing countries often have early or precocious puberty, requirin...
Context: Isolated heterozygous SHOX defects are the most frequent monogenic cause of short stature, ...
Object To study the outcomes of GnRHa on final adult height in Chinese idiopathic central precocious...
OBJECTIVE:Gonadotropin-releasing hormone agonists (GnRHa) are the treatment of choice for central pr...
Objectives: To study the effect of gonadotropin-releasing hormone analogue (GnRHa) on final adult he...
Context: GH treatment is effective in improving height in short children born small for gestational ...
Context:GH treatment is effective in improving height in short children born small for gestational a...
Context: GH treatment is effective in improving height in short children born small for gestational ...
Objective: We assessed in a retrospective unicenter study the impact of treatment with GnRH analogs ...
BACKGROUND/PURPOSE: It has been reported that gonadotropin releasing hormone analogue (GnRHa) therap...
Objective: To assess the long-term effect of prepubertal high-dose GH treatment on growth in childre...
To assess whether delaying puberty may improve final height in GH-deficient children with a poor hei...
It has been reported that gonadotropin releasing hormone analogue (GnRHa) therapy can improve the ad...
Background/PurposeIt has been reported that gonadotropin releasing hormone analogue (GnRHa) therapy ...
Context: Several factors can affect adult height (AH) of patients with gonadotropin-dependent precoc...
Background: Girls adopted from developing countries often have early or precocious puberty, requirin...
Context: Isolated heterozygous SHOX defects are the most frequent monogenic cause of short stature, ...
Object To study the outcomes of GnRHa on final adult height in Chinese idiopathic central precocious...