Add to ORKGPlaque rupture and subsequent thrombosis at the site ofthe plaque rupture is the most common underlying patho-physiological mechanism of acute coronary syndromes [1]. The clinical manifestations of acute coronary syndromes are sudden cardiac death, acute myocardial infarction and unstable angina. Approximately 90 % of cases of non-fatal myocardial infarction and many cases of sudden cardiac death are caused by the rupture of a coronary atherosclerotic plaque [2]. Plaque rupture may be precipitated by external stresses or ‘triggers ’ imposed on coronary plaques [3]. It is important to differentiate between intrinsic long-term changes of coronary plaques, internal triggering mecha-nisms and external triggers (Figure 1). Intrinsic long-term ch...
Atherosclerotic diseases and their thrombotic complications remain the leading causes of mortality a...
Experimental models of atherogenesis have provided a growing body of information about molecular mec...
AbstractThe propensity of plaque to disrupt is a major determinant of future ischemic events. Althou...
The treatment of acute coronary syndromes, including acute myocardial infarction and unsta-ble angin...
Atherosclerotic luminal narrowing is determined by plaque mass and local change in vessel size (remo...
Well into the 21st century, we still triage acute myocardial infarction on the basis of the presence...
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coro...
Experimental models of atherogenesis have provided a growing body of information about molecular mec...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
The pathophysiology of acute coronary syndromes involves spontaneous or mechanical disruption of ath...
In the last twenty years, our comprehension of the molecular mechanisms involved in the formation, p...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
Atherosclerotic diseases and their thrombotic complications remain the leading causes of mortality a...
Experimental models of atherogenesis have provided a growing body of information about molecular mec...
AbstractThe propensity of plaque to disrupt is a major determinant of future ischemic events. Althou...
The treatment of acute coronary syndromes, including acute myocardial infarction and unsta-ble angin...
Atherosclerotic luminal narrowing is determined by plaque mass and local change in vessel size (remo...
Well into the 21st century, we still triage acute myocardial infarction on the basis of the presence...
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coro...
Experimental models of atherogenesis have provided a growing body of information about molecular mec...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
The pathophysiology of acute coronary syndromes involves spontaneous or mechanical disruption of ath...
In the last twenty years, our comprehension of the molecular mechanisms involved in the formation, p...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
In the last twenty years, our comprehension of the molecular mechanisms involved in formation, progr...
Atherosclerotic diseases and their thrombotic complications remain the leading causes of mortality a...
Experimental models of atherogenesis have provided a growing body of information about molecular mec...
AbstractThe propensity of plaque to disrupt is a major determinant of future ischemic events. Althou...