ARTICLES Association of Volume and Volume-Independent Factors With Accuracy in Screening Mammogram Interpretation

Background: Early detection of breast cancer is associated with the accurate reading of screening mammograms, but factors that influence reading accuracy are not well under-stood. We thus investigated whether reading volume and other factors were independently associated with accuracy in reading screening mammograms in a population of U.S. radiologists. Methods: A random selection of 110 of 292 ra-diologists who agreed to participate, if selected, interpreted screening mammograms from 148 randomly selected women. Original index mammograms (i.e., mediolateral ob-lique and craniocaudal views of each breast) were used; comparison original mammograms were provided when available. Radiologist-level and facility-level factors were surveyed. Two standard metrics of screening accuracy, both based on receiver operating characteristic curves, were ana