Summary

odontal tissues as well as metabolic processes in bone tissue of the alveolar crest are closely related to the intensity of systemic metabolic processes and to the inner bone reorganization in the whole skeleton. Investigations revealed the influence of systemic factors (such as impaired homeostasis of main calcium-regulating hormones and disorders in bone tissue metabolism) on the activity of destructive and resorbtive processes in the alveolar bone. Materials and methods: 32 patients (18 women and 14 men) with generalized II–III ° periodontitis in the period of disease exacerbation were examined clinically, roentgenologically and by laboratory testings. The control group included 13 patients in the initial grade of periodontitis or without clinical and roentgenological changes in periodontal tissues. Blood levels of the main calcium-regulating hormones such as parathyroid hormone and calcitonin as well as of the biochemical markers o