Invasive Candida species infection: the importance of adequate empirical antifungal therapy

Candida species are a common cause of bloodstream and invasive infection in critically ill and immu-nosuppressed patients. Furthermore, invasive Candida infection carries a poor prognosis and may initially be mistaken for bacterial infection. An article in this issue of the Journal investigates the relationship between adequacy of initial empirical therapy and outcome from invasive Candida infec-tion. This study shows that adequate empirical therapy is received by only a quarter of patients, and that inappropriate therapy is associated with increased mortality. These findings highlight the import-ance of appropriate empirical therapy in invasive Candida infection