Summary:Theestimationofmodelparameters fromexperimental data remains a bottleneck for a major breakthrough in systems biology. We present a Systems Biology Markup Language (SBML) based ParameterEstimationTool (SBML-PET). The tool is designed to enable parameter estimation for biological models including signaling path-ways, gene regulation networks and metabolic pathways. SBML-PET supports import and export of the models in the SBML format. It can estimate the parameters by fitting a variety of experimental data fromdifferentexperimental conditions.SBML-PEThasaunique feature of supporting event definition in the SMBL model. SBML models can alsobesimulated inSBML-PET.StochasticRankingEvolutionStrategy (SRES) is incorporated in SBML-PET for p...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Computational models can help researchers to interpret data, understand biological functions, and ma...
The estimation of model parameters from experimental data remains a bottleneck for a major breakthro...
Summary: The estimation of model parameters from experimental data remains a bottleneck for a major ...
Summary: Parameter estimation is crucial for the modeling and dynamic analysis of biological systems...
Summary: Parameter estimation is crucial for the modeling and dynamic analysis of biological systems...
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, th...
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, th...
In systems biology, biological phenomena are often modeled by Ordinary Differential Equations (ODEs)...
A cornerstone of systems biology is the use of computational modeling, by which hypotheses can be ca...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
BACKGROUND: Systems Biology Markup Language (SBML) is the standard model representation and descript...
Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of comp...
With the rise of Systems Biology as a new paradigm for understanding biological processes, the devel...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Computational models can help researchers to interpret data, understand biological functions, and ma...
The estimation of model parameters from experimental data remains a bottleneck for a major breakthro...
Summary: The estimation of model parameters from experimental data remains a bottleneck for a major ...
Summary: Parameter estimation is crucial for the modeling and dynamic analysis of biological systems...
Summary: Parameter estimation is crucial for the modeling and dynamic analysis of biological systems...
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, th...
Reproducibility and reusability of the results of data-based modeling studies are essential. Yet, th...
In systems biology, biological phenomena are often modeled by Ordinary Differential Equations (ODEs)...
A cornerstone of systems biology is the use of computational modeling, by which hypotheses can be ca...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
BACKGROUND: Systems Biology Markup Language (SBML) is the standard model representation and descript...
Abstract Systems biology has experienced dramatic growth in the number, size, and complexity of comp...
With the rise of Systems Biology as a new paradigm for understanding biological processes, the devel...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Systems biology has experienced dramatic growth in the number, size, and complexity of computational...
Computational models can help researchers to interpret data, understand biological functions, and ma...