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uta mb ate developmental ability of cloned embryos derived from cultured neural stem cell (NSC) nuclei and compared the success rate with that of embryos cloned from other donor cells such as differentiated NSCs, cumulus cells, Sertoli cells and ES cells in the mouse. success rates of animal cloning from adult somatic cells are consistently low. Although we have tried to improve higher (12.3–33%) than the rates for other differentiated Cheong et al. (1993) and Hiiragi & Solter (2005) found that the developmental stage of donor embryos affects a somatic cell lineage. Consistent with this hypothesis, donor cells (Wakayama et al. 1999, Rideout et al. 2000,DOI: 10.1530/rep.1.01010Jeanisch et al. 2002). Inoue et al. (2005) have also q 2006 Society for Reproduction and FertilityInoue et al. (2006) also used adult hematopoietic stem cells (HSCs) in the mouse. Although they generatedthe success rate of cloning in the mouse, usually fewer than 3 % of the cloned embryos develop to term whe