The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily ’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily groups together domains of different families which have a common evolutionary ancestor based on structural, functional and sequence data. SUPERFAMILY domain assignments are gener-ated using an expert curated set of profile hidden Markov models. All models and structural assign-ments are available for browsing and download fro
Here we assessed the use of domain families for predicting the functions of whole proteins. These 'f...
Abstract: Investigations into the origins and evolution of regulatory mechanisms re-quire quantitati...
Functional annotation of a protein sequence in the absence of experimental data or clear similarity ...
10 The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily ’ level, f...
SUPERFAMILY provides structural, functional and evolutionary information for proteins from all compl...
The SUPERFAMILY hidden Markov model library repre-senting all proteins of known structure predicts t...
The SUPERFAMILY resource provides protein domain assignments at the structural classification of pro...
Several proteins that have substantially diverged during evolution retain similar three-dimensional ...
Here, we present a major update to the SUPERFAMILY database and the webserver. We describe the addit...
Automatic identification and annotation of protein domains is a major challenge for genome sequencin...
Members of a superfamily of proteins could result from divergent evolution of homologues with insign...
Modern gene sequencing methods and the genome projects have been depositing data in the public datab...
Genome sequencing and structural genomics projects are providing new insights into the evolutionary ...
The completion of a substantial number of complete genome sequencing initiatives has produced more t...
Protein family databases are an important resource for biologists seeking to characterise the functi...
Here we assessed the use of domain families for predicting the functions of whole proteins. These 'f...
Abstract: Investigations into the origins and evolution of regulatory mechanisms re-quire quantitati...
Functional annotation of a protein sequence in the absence of experimental data or clear similarity ...
10 The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily ’ level, f...
SUPERFAMILY provides structural, functional and evolutionary information for proteins from all compl...
The SUPERFAMILY hidden Markov model library repre-senting all proteins of known structure predicts t...
The SUPERFAMILY resource provides protein domain assignments at the structural classification of pro...
Several proteins that have substantially diverged during evolution retain similar three-dimensional ...
Here, we present a major update to the SUPERFAMILY database and the webserver. We describe the addit...
Automatic identification and annotation of protein domains is a major challenge for genome sequencin...
Members of a superfamily of proteins could result from divergent evolution of homologues with insign...
Modern gene sequencing methods and the genome projects have been depositing data in the public datab...
Genome sequencing and structural genomics projects are providing new insights into the evolutionary ...
The completion of a substantial number of complete genome sequencing initiatives has produced more t...
Protein family databases are an important resource for biologists seeking to characterise the functi...
Here we assessed the use of domain families for predicting the functions of whole proteins. These 'f...
Abstract: Investigations into the origins and evolution of regulatory mechanisms re-quire quantitati...
Functional annotation of a protein sequence in the absence of experimental data or clear similarity ...