RESEARCH Carbohydrate co-ingestion n

Full list of author information is available at the end of the articlestrength, which reduces functional capacity and increases the risk of developing chronic metabolic diseases [1]. Re-cent work suggests that with ageing skeletal muscle tissue becomes less sensitive to the main anabolic stimuli, i.e. food intake and physical activity [2-5]. The proposed blunted muscle protein synthetic response to protein in-gestion, coined “anabolic resistance”, has been suggested to represent a key factor responsible for the progressive dietary strategies that stimulate post-prandial muscle pro-tein synthesis [7-9]. Dietary protein has been identified as the main factor driving the muscle protein synthetic re-sponse to food intake [10]. However, other macronutrients may modulate the post-prandial muscle protein synthetic response to protein ingestion. Previous work suggests that carbohydrate co-ingestion with protein stimulates post-prandial muscle protein accretion [10-14]. The latter could be attributed to the higher energy intake and/or the greater post-prandial insulin release following carbohydrate co-ingestion. I