from babesiosis

Antithrombin III (AT III) was measured in 15 dogs with Babesia canis infection and in 15 healthy dogs. Blood samples for control group and patients were taken before the therapy with imidocarb dipropionat and on the 1st and 5th days after the therapy. Measurements of AT III activity in canine plasma with thrombin dependent chromogenic substrate assay using automatic analyzer showed a good within-run precision. The results were expressed as proportions of the norm. Value for AT III before the therapy was lower than in the control group. Activity of AT III was higher on the post-treatment day 5 than before the therapy. A survey of individual data demonstrated that in 2 dogs the pre-treatment AT III values were 0.66 and 0.79, respectively, showing consumption inhibitors of coagulation. Key words: babesiosis, dog, antithrombin II