studies have demonstrated that statins, in addition to their lipid-lowering effects, have anti-inflam-matory and immunomodulatory properties [1]. These properties of statins have suggested that they could have beneficial effects in immune mediated neurological disorders [2, 3]. In particular, lovastatin has been shown to in-hibit the induction of inducible nitric oxide synthase and proin-flammatory cytokines in rat astro-cytes, microglia and macrophages [2] and to repress MHC-II medi
Statins, the inhibitors of HMG-CoA reductase, are currently among the most commonly prescribed agent...
The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, statins, are potent inhibi...
The modulation of undesirable immune responses is a novel and exciting property of statins. These dr...
Abstract Since contradictory findings have been reported on potential effects of statins in modulati...
Abstract Based on their potent anti-inflammatory properties and a preliminary clinical trial, statin...
Since contradictory findings have been reported on potential effects of statins in modulating the in...
Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-Co...
HMG-CoA reductase inhibitors, or statins, are potent plasma LDL-cholesterol (LDL-c) lowering agents....
Microglial cells, upon hyperactivation, produce proinflammatory cytokines and other oxidative stress...
Anti-inflammatory and immunomodulatory effects of statins. 3-Hydroxy-3-methyl-gutaryl coenzyme A (HM...
There is growing interest in drug repositioning to find new therapeutic indications for drugs alread...
Statins are among the most prescribed drugs in recent clinical practice. They are also known for the...
Besides the well-known lipid-lowering effect, statins display nonlipid-lowering pharmacological acti...
The statins, a group of inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are repor...
Abstract—Statins have long been thought to exert their benefits by reducing cholesterol synthesis. H...
Statins, the inhibitors of HMG-CoA reductase, are currently among the most commonly prescribed agent...
The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, statins, are potent inhibi...
The modulation of undesirable immune responses is a novel and exciting property of statins. These dr...
Abstract Since contradictory findings have been reported on potential effects of statins in modulati...
Abstract Based on their potent anti-inflammatory properties and a preliminary clinical trial, statin...
Since contradictory findings have been reported on potential effects of statins in modulating the in...
Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-Co...
HMG-CoA reductase inhibitors, or statins, are potent plasma LDL-cholesterol (LDL-c) lowering agents....
Microglial cells, upon hyperactivation, produce proinflammatory cytokines and other oxidative stress...
Anti-inflammatory and immunomodulatory effects of statins. 3-Hydroxy-3-methyl-gutaryl coenzyme A (HM...
There is growing interest in drug repositioning to find new therapeutic indications for drugs alread...
Statins are among the most prescribed drugs in recent clinical practice. They are also known for the...
Besides the well-known lipid-lowering effect, statins display nonlipid-lowering pharmacological acti...
The statins, a group of inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase, are repor...
Abstract—Statins have long been thought to exert their benefits by reducing cholesterol synthesis. H...
Statins, the inhibitors of HMG-CoA reductase, are currently among the most commonly prescribed agent...
The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, statins, are potent inhibi...
The modulation of undesirable immune responses is a novel and exciting property of statins. These dr...