Acta med Nagasaki. 18: 35-37 Interstitial Cell-Stimulating Hormone Activities in the Pituitary Gland and Peripheral Blood of Immature and Mature Male Dogs

Investigations have been made of the interstitial cell-stimulating hormone (ICSH) activity of the canine pituitary and plasma at different ages. A fairly high activity of IC-SH in the pituitary of 3 weeks old animals was observed. At 2 months old the ICSH ac-tivity was about twice as high as that in the pituitary of 3 weeks old animals, in potency per mg of tissue weight. However, a somewhat lower activity was found for 2 years old animals than for 2 months old animals. In plasma samples from 3 weeks old and 2 mon-ths old animals, no detectable ICSH activity was found but measurable activity was detec-ted in samples from 2 years old animals