Cancer–Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic

hereas cancer cells alone, or their coculture with PSCs, sup-pressed it. CONCLUSIONS: Although PSCs are the dominant producers of VEGF and increase endothelial cell growth in vitro, in the peritumoral stroma, they contribute to the atrix deposition and by amplifying endostatin production of Neoplasia (2009) 11, 497–508 Abbreviati; PCC creatic stellate cel Address al chnisc