DATABASE • ACTIVE PRINCIPLES IN INDIAN MEDICINAL PLANTS

Plants represent the eternal kindness of nature by all means which is really expressed in varied human culture from time immemorial. Many of the modern medicines are produced indirectly from medicinal plants, for example aspirin. Medicinal plants can provide biologically active molecules and lead structures for the development of modified derivatives with enhanced activity and /or reduced toxicity. Drug development based on natural product is an important and fast growing area due to the limitations of developing new synthetic molecules based on the principle of active components or pure chemicals.The scientific study of traditional medicines, derivation of drugs through bioprospecting and systematic conservation of the concerned medicinal plants are thus of great importance.In order to improve the information about active principles we created a APMP (Active Principles in Indian Medicinal Plants) database with textual and graphical based web applications.The database was developed as relational database which incorporates the structural information and annotated data of active constituents, toxicological, biochemical, pharmacological activity and technical data. APMP provides an external links to online databases and internal links every active principle which contains molecular descriptors, SMILES notation as well as for each plan