This study was prompted by the growing interest in and demand for non-opiate alternatives to methadone detoxification, such as the 2-adrenergic agonist lofexidine. Lofexidine acts centrally to suppress the opiate withdrawal syndrome and offers a non-opiate, rapid withdrawal treatment from opiates, without the risk of dependency. The study aims to identify an appropriate alternative model for a Community Detoxification Team for implementation in Clondalkin, an urban area where there are high levels of opiate misuse. The review of the relevant literature provided a conceptual and practical base of knowledge to inform the study. The review found that lofexidine can be used safely in a community stetting and therefore could provide a viable, sa...
Background: In the United Kingdom (UK), there is an extensive market for the class 'A' drug heroin a...
The efficacy of lofexidine/naloxone was compared with lofexidine/placebo in a double-blind, randomiz...
Despite the record breaking levels of opiate related deaths published this year in the UK, pharmacol...
This study was prompted by the growing interest in and demand for non-opiate alternatives to methado...
Abstract Background Heroin is a synthetic opioid with an extensive illicit market leading to large n...
Buprenorphine/naloxone, methadone and lofexidine are medications with utility in the treatment of op...
Objective: In-treatment and post-treatment outcomes were compared for three detoxification procedure...
The aim of the present study is to evaluate lofexidine and clonidine, in an accelerated opiate detox...
OBJECTIVE: In-treatment and post-treatment outcomes were compared for three detoxification procedure...
The national community detoxification programme is a supported, structured outpatient detoxification...
The physical, psychological and social implications of opiate dependency are well known. A variety o...
A pilot study was performed to assess the effectiveness of treatment in an opioid dependent populati...
Transitioning opioid-dependent patients from detoxification to long-term treatment: efficacy of inte...
This study compares two methods of detoxification available to heroin users in Western Australia: cl...
This report draws from extensive literature on subscribing prescribing for opiate dependence, and fo...
Background: In the United Kingdom (UK), there is an extensive market for the class 'A' drug heroin a...
The efficacy of lofexidine/naloxone was compared with lofexidine/placebo in a double-blind, randomiz...
Despite the record breaking levels of opiate related deaths published this year in the UK, pharmacol...
This study was prompted by the growing interest in and demand for non-opiate alternatives to methado...
Abstract Background Heroin is a synthetic opioid with an extensive illicit market leading to large n...
Buprenorphine/naloxone, methadone and lofexidine are medications with utility in the treatment of op...
Objective: In-treatment and post-treatment outcomes were compared for three detoxification procedure...
The aim of the present study is to evaluate lofexidine and clonidine, in an accelerated opiate detox...
OBJECTIVE: In-treatment and post-treatment outcomes were compared for three detoxification procedure...
The national community detoxification programme is a supported, structured outpatient detoxification...
The physical, psychological and social implications of opiate dependency are well known. A variety o...
A pilot study was performed to assess the effectiveness of treatment in an opioid dependent populati...
Transitioning opioid-dependent patients from detoxification to long-term treatment: efficacy of inte...
This study compares two methods of detoxification available to heroin users in Western Australia: cl...
This report draws from extensive literature on subscribing prescribing for opiate dependence, and fo...
Background: In the United Kingdom (UK), there is an extensive market for the class 'A' drug heroin a...
The efficacy of lofexidine/naloxone was compared with lofexidine/placebo in a double-blind, randomiz...
Despite the record breaking levels of opiate related deaths published this year in the UK, pharmacol...