diabetes mellitus

mellitus Abstract The genetic makeup that individuals inherit from their ancestors is re-sponsible for variation in responses to food and susceptibility to chronic diseases such as Type 2 diabetes mellitus (T2DM). Common variations in gene sequences, such as single nucleotide polymorphisms, produce differences in complex traits such as height or weight potential, food metabolism, food-gene interactions, and disease susceptibilities. Nutritional genomics, or nutrigenomics, is the study of how foods af-fect the expression of genetic information in an individual and how an individual’s genetic makeup affects the metabolism and response to nutrients and other bioac-tive components in food. Since both diet and genes alter one’s health and suscepti-bility to disease, identifying genes that are regulated by diet and that cause or contribute to chronic diseases could result in the development of diagnostic tools